Welcome to
iNEXT-Discovery

2nd Annual Scientific Meeting

August 29-30, 2022

Warsaw, Poland

The aim of the iNEXT-Discovery Annual Scientific Meeting is to showcase the recent discoveries in structural biology highlighting the developments in technology and applications. The talks will be presented by external speakers and iNEXT-Discovery infrastructure users.

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Add to My Calendar 2022-04-11 09:30:00 2022-04-13 14:00:00 Europe/Warsaw iNEXT-Discovery Annual Scientific Meeting iNEXT-Discovery Annual Scientific Meeting International Institute of Molecular and Cell Biology in Warsaw inext@iimcb.gov.pl

KEYNOTE SPEAKERS

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Brenda Schulman

Max Planck Institute of Biochemistry, Germany
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Leonid Sazanov

Institute of Science and Technology, Austria

Brenda Schulman received her PhD from MIT before doing postdoctoral work at MGH Cancer Center and at Memorial Sloan-Kettering Cancer Center. In 2001, she joined the faculty at St. Jude Children’s Research Hospital where she retains an adjunct faculty position. She was an HHMI Investigator and the Joseph Simone Chair in Basic Research at St. Jude until July 2017, when she moved to the Max Planck Institute of Biochemistry, where she is a Director and Scientific Member. She has won a number of awards including the Leibniz Prize and the Ernst Jung Prize in Medicine, and is a member of the American Academy of Arts and Sciences, the National Academy of Sciences, and EMBO.

Leonid Sazanov is a Professor at the Institute of Science and Technology Austria. He is an expert in the structural biology of membrane proteins, especially those from the domain of bioenergetics, including respiratory complex I. He is member of Royal Society and EMBO.

SPEAKERS

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Daren Fearon

Diamond Light Source, England
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Svetlana Pylaeva

Paderborn University, Germany
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Matthias Geyer

University of Bonn, Germany
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Arwen Pearson

Universität Hamburg, Germany
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Sebastian Glatt

Malopolska Centre of Biotechnology, Poland avatar

Jakub Szlachetko

National Synchrotron Radiation Centre SOLARIS, Poland
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Roman Jerala

Kemijski inštitut, Slovenia

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Markus Weingarth

Utrecht University, The Netherlands
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Meindert Lamers

Leiden University Medical Center, The Netherlands avatar

Jan Wollenhaupt

Helmholtz-Zentrum Berlin, Germany

PROGRAM

02:00 PM

Anastassis Perrakis - Opening Remarks

Scientific session Chair: Marcin Nowotny

Coiled-coil motifs for the design of cellular logic circuits and new protein folds

Roman Jerala

02:30 PM

tRNAslational control by tRNA modification enzymes

Sebastian Glatt

03:00 PM

T-REXX: a dedicated endstation for time-resolved macromolecular crystallography

Arwen Pearson

03:30 PM

BREAK

04:00 PM

Scientific session Chair: Grzegorz Dubin

Eight structures of MutS during DNA mismatch repair

Meindert Lamers

04:30 PM

Mechanisms of lipid-targeting antibiotics

Markus Weingarth

05:00 PM

Open science discovery of SARS-CoV-2 antivirals

Daren Fearon

05:30 PM

Poster session & Refreshment

Only in stationary form

06:00 PM - 08:00 PM

Scientific session Chair: Manfred Weiss

Molecular machines in the membrane: structures and mechanisms of the respiratory chain components

Leonid Sazanov

09:00 AM

Short talks selected from posters - part I

10:00 AM

Cofee break

11:00 AM

Frag4Lead – First Step from Crystallographic Fragment Hits to Improved Binders

Jan Wollenhaupt

11:15 AM

Identification of a new target site: Cryo-EM structure of NLRP3 bound to CRID3

Matthias Geyer

11:35 AM

Investigating Novel Mixed Valence DNP Radicals for in-cell NMR and beyond

Svetlana Pylaeva

11:55 AM

Lunch break

12:15 PM

Scientific session Chair: Anastassis Perrakis

SOLARIS synchrotron infrastructure for biomedical research

Jakub Szlachetko

01:15 PM

Short talks selected from posters – part II

01:45 PM

Keynote Lecture - Visualizing ubiquitin ligation

Brenda Schulman

02:30 PM

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CONTACT

inext@iimcb.gov.pl

International Institute of Molecular
and Cell Biology in Warsaw
4 Ks. Trojdena Street
02-109 Warsaw, Poland

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VENUE

IBIB Conference Centre
4 Ks. Trojdena Street
02-109 Warsaw, Poland

 


Scientific Organizing Committee

Grzegorz Dubin

Marcin Nowotny

Anastassis Perrakis

Manfred Weiss

Hans Wienk

Local Organizing Team

Marcin Nowotny

Alexia Danyłow

Daria Goś

Agnieszka Potęga

Jakub Skaruz

Małgorzata Sroka

Małgorzata Staszkowska-Wągrodzka

Justyna Szopa